Efficacy of a Topical Gelatin-Thrombin Matrix Sealant in Reducing Postoperative Drainage Following Anterior Cervical Discectomy and Fusion

STUDY DESIGN: Retrospective fusion level(s)-, age-, and gender-matched analysis. PURPOSE: To determine whether the application of a topical gelatin-thrombin matrix sealant (Floseal) at the end of anterior cervical discectomy and fusion (ACDF) can reduce the amount of postoperative hemorrhage. OVERVIEW OF LITERATURE: The effect of the matrix sealant in decreasing postoperative hemorrhage following ACDF has not been reported. METHODS: Matrix sealant was (n=116, study group) or was not applied (n=58, control group) at the end of ACDF. Patients were selected by 1:2 matching criteria of fusion level(s), age, and gender. Seven parameters described below were compared between the two groups. RESULTS: The total drain amount for the first 24 hours (8+/-9 versus 27+/-22 mL), total drain amount until the 8-hour drainage decreased to < or =10 mL (8+/-10 versus 33+/-26 mL), and the total drain amount until 6 AM on the first postoperative day (7+/-8 versus 24+/-20 mL) were significantly lower in the study group than the control group (all p<0.001). The time for the 8-hour drainage to decrease to < or =10 mL was significantly lower in the study group (10+/-5 versus 26+/-14 hours, p<0.001). The 8-hour drainage decreased to < or =10 mL on the operation day in most patients (88%) in the study group versus mostly on the first (48%) or second (33%) postoperative day in the control group (p<0.001). The total drain amount until 6 AM on the first postoperative day was 0 mL in 43% of patients in the study group and in 7% in the control group (p<0.001). No patient in either group required hematoma evacuation. CONCLUSIONS: Application of the topical matrix sealant at the end of ACDF can significantly reduce the amount of postoperative hemorrhage.

Short to Midterm Results of Bernese Periacetabular Osteotomy for Hip Dysplasia / 대한정형외과학회잡지

PURPOSE: The goal of this study was to analyze the short to midterm results of Bernese periacetabular osteotomy for the patient with hip dysplasia. MATERIALS AND METHODS: Fourteen Bernese periacetabular osteotomies were performed in 13 patients and were followed-up for more than 2.5 years. All patients had been treated at Department of Orthopedic Surgery, Seoul National University Hospital from June 1998 to December 2007. We conducted an interview and asked the patients to complete the Harris hip score and pain visual analogue scale (VAS) score for clinical evaluation. Radiographic measurements included Tonnis osteoarthritis grade, center-edge angle of Wiberg, acetabular angle of Sharp, acetabular depth index, acetabular head index. RESULTS: Mean Harris hip score improved from 63.8 points preoperatively to 82.9 points postoperatively and pain VAS score improved from 7.6 points preoperatively to 0.8 points postoperatively. Based on Tonnis osteoarthritis grade, progression of osteoarthritis was found in 4 hips. Radiologically, center-edge angle of Wiberg, acetabular angle of Sharp, acetabular depth index and acetabular head index improved. Complications included superficial skin infection in one hip and non-union of pubic ramus in one. One patient had metal hypersensitivity to cortical screws and fracture of posterior column. CONCLUSION: The short to midterm results show Bernese periacetabular osteotomy is a satisfactory technique for treating early and mild hip-osteoarthritis patients with hip dysplasia clinically and radiographically.